Nboost Doctor brochure - Flipbook - Page 16
Observed effects: Preventative bene昀椀ts1
% CHANGE AFTER 28 DAYS OF NBOOST TREATMENT:
Thickness of the epidermis
0%
10%
20%
30%
40%
50%
60%
12,0%
Nboost improves
epidermal thickness
and density to temporally
correct the soft tissue
de昀椀cit
Density of the epidermis
0%
10%
20%
30%
40%
50%
60%
57,7%
RESULTS MEASURED BY HF ULTRASOUND IMAGEING DEVICE.
Nboost
vs control
+107%
control
boost
Ki-67 protein is present during all active phases of the cell cycle (G1, S, G2,
and mitosis), but is absent from resting cells (G0), making it an excellent marker
for determining the so-called growth fraction of a given cell population.2
Nboost contributes to induce mechanical stress3 helping
to maintain the skin homeostasis and supporting regeneration.
1. Płatkowska, A.; Korzekwa, S.; Łukasik, B.; Zerbinati, N. Combined Bipolar Radiofrequency and Non-Crosslinked Hyaluronic Acid Mesotherapy Protocol to Improve Skin Appearance
and Epidermal Barrier Function: A Pilot Study. Pharmaceuticals 2023, 16, 1145. https://doi.org/10.3390/ph16081145.
2. Scholzen T, Gerdes J. The Ki-67 protein: from the known and the unknown. J Cell Physiol. 2000 Mar;182(3):311-22. doi: 10.1002/(SICI)1097-4652(200003)182:3
3.0.CO;2-9.
PMID: 10653597.
3. Mei-fang Wang a, Jun-ying Zhaoa, and Lin-feng Lia; Evaluation of changes in skin biophysical parameters and appearance after pneumatic injections of non-cross-linked hyaluronic
acid in the face; JOURNAL OF COSMETIC AND LASER THERAPY 2018, VOL. 20, NOS. 7–8, 454–461.
4. Wallace L, Roberts-Thompson L, Reichelt J. Deletion of K1/K10 does not impair epidermal stratification but affects desmosomal structure and nuclear integrity. J Cell Sci. 2012 Apr
1;125(Pt 7):1750-8. doi: 10.1242/jcs.097139. Epub 2012 Feb 28. PMID: 22375063. 5. Zhang X, Yin M, Zhang LJ. Keratin 6, 16 and 17-Critical Barrier Alarmin Molecules in Skin Wounds and
Psoriasis. Cells. 2019 Aug 1;8(8):807. doi: 10.3390/cells8080807. PMID: 31374826; PMCID: PMC6721482.
