Brochure Fillers - Flipbook - Page 17
Facial aging is a composite, interrelated, three-dimensional
process involving changes to the bone, soft tissue and skin.
It is a complex, multifaceted process where a change in one layer
often causes a cascade of changes to adjacent layers.5
Facial bones serve as the foundation for soft tissue attachment, ensuring stability and structure.5
With aging, bones changes lead to soft tissue repositioning and recession.5
Lateral orbital
Superior orbital
Inferior orbital
Medial
Nasolabial
Middle
Lateral
temporal-cheek
Fat pads and muscles undergo an inferior and medial repositioning as they adjust to the shifting bony foundation.5
Deep fat atrophies, while superficial fat tends to reposition or hypertrophy.5
Common observations include fat atrophy in superficial fat compartments of the forehead, periorbital and perioral regions.5
1. Haydont V, Bernard BA and Fortunel NO. Age-related evolutions of the dermis: clinical signs, fibroblast and extracellular matrix dynamics. Mech Ageing Dev. 2019 Jan;177:150-156.
https://doi.org/10.1016/j.mad.2018.03.006
2. Kapoor KM, Saputra DI, Porter CE, Colucci L, Stone C, Brenninkmeijer EEA, Sloane J, Sayed K, Winaya KK and Bertossi D. Treating aging changes of facial anatomical layers
with Hyaluronic Acid fillers. Clin Cosmet Investig Dermatol. 2021 Aug 26;14:1105-1118. https://doi.org/10.2147/CCID.S294812
3. Lee D, Cheon C, Son S., Kim YZ, Kim JY, JANG J and Kim SS. Influence of molecular weight on swelling and elastic modulus of Hyaluronic Acid dermal fillers.
Polymer Korea. 2015, 39, 976-980. https://doi.org/HYPERLINK “http://dx.doi.org/10.7317/pk.2015.39.6.976”10.7317/pk.2015.39.6.976
4. Clinical data on file.
5. Swift A, Liew S, Weinkle S, Garcia JK and Silberberg MB, The Facial Aging Process From the “Inside Out”, Aesthetic Surgery Journal, Volume 41, Issue 10, October 2021, Pages 1107–1119,
https://doi.org/10.1093/asj/sjaa339
Pictures powered by Centro Medico Polispecialistico Srl.
