Exe Brochure Zaffiro 28022024 WEB - Flipbook - Page 7
Physiological
Bio-Stimulation
Smart Infrared works by delivering precise
thermal energy to dermis, activating fibroblasts,
the key cellular drivers of collagen production.
This controlled stimulation initiates a cascade
of dermal remodeling processes, improving
skin structure and elasticity naturally, while
promoting angiogenesis, essential for skin
rejuvenation.
Over time, collagen regeneration strengthens
the extracellular matrix, restoring the skin’s
youthful firmness and texture.
Collagenesis
Histological picture of collagen redensification
(Trichrome Masson staining) after Zaffiro session courtesy of Dr Kubik.
FIBROBLAST ACTIVATION*
Vimentin
5
4
3
2
1
0
before
Representative vimentin expression, from left to right: immediately before the procedure;
5 days after the procedure; 21 days after the procedure. magnification 20x.
ANGIOGENESIS*
5 days
after
21 days
after
CD31
1.5
1.0
0.5
0.0
Representative CD31 expression, from left to right: immediately before the procedure;
5 days after the procedure; 21 days after the procedure. magnification 20x.
* Data on file.
before
5 days
after
21 days
after
