SCIENCE-BOOK 29.04.2025 - Flipbook - Page 3
Fillers PEG: A REVOLUTION IN HA FILLER MARKET
Neauvia’s R&D designed monophasic and cohesive hydrogels with distinctive properties and gel consistencies. Neauvia PEG-HA
Fillers are based on a unique Smart Crosslinking Technology - SXT - combining HA and PEG. This gives outstanding mechanical,
rheological and thermodynamic properties to the Neauvia’s portfolio, ensuring a high safety profile.1,2,3,4,5
INTENSE LINE
STIMULATE LINE
Crosslinked with PEG enriched with GLYCINE and L-PROLINE
Crosslinked with PEG enriched with GLYCINE, L-PROLINE and CaHA
HYDRO DELUXE LINE
Non-crosslinked enriched with GLYCINE, L-PROLINE and CaHA
Intense Rheology, Intense Flux, Intense LV, Intense, Intense Lips, Intense Man, Stimulate, Stimulate Man, Hydro Deluxe and Hydro Deluxe Man are class III medical devices regulated under the EU MDR 2017/745 Regulation. Intense Rose is a class III medical device
regulated under the EU MDD 93/42 Directive. Manufacturer: MATEX LAB SPA, via Carlo Urbani 2 ang. via Enrico Fermi, Brindisi, Italy. Please carefully read the instructions in the leaflets. The use of these products requires the intervention of a healthcare professional.
Only to be used by physicians in accordance with local legislation, trained in the injection techniques on Hyaluronic Acid based. Each patient may react differently to the treatment based on (but not limited to) medical history, genetics, age, sex, personal
motivation, lifestyle, and other factors. 1. Marino F, Cosentino M, Legnaro M, Luini A, Sigova J, Mocchi R, Lotti T and Zerbinati N. Immune profile of Hyaluronic Acid hydrogel Polyethylene Glycol crosslinked: an in vitro evaluation in human polymorphonuclear
leukocytes. Dermatologic Therapy. 2020; e13388. https://doi.org/10.1111/dth.1338. 2. Clinical data on file. 3. Zerbinati N, Lotti T, Monticelli D, Rauso R, González-Isaza P, D’Este E, Calligaro A, Sommatis S, Maccario C, Mocchi R, Lotti J, Wollina U, Tchernev G
and França K. In vitro evaluation of the biosafety of Hyaluronic Acid PEG cross-linked with micromolecules of Calcium Hydroxyapatite in low concentration. Open Access Maced J Med Sci.https://doi.org/10.3889/oamjms.2018.044. 4. Zerbinati N, Capillo
MC, Sommatis S, Maccario C, Alonci G, Rauso R, Galadari H, Guida S and Mocchi R. Rheological investigation as tool to assess physicochemical stability of a Hyaluronic Acid dermal filler cross-linked with Polyethylene Glycol Diglycidyl Ether and containing
Calcium Hydroxyapatite, Glycine and L-Proline. Gels 2022, 8,264. https://doi.org/10.3390/gels8050264. 5. Zerbinati N, Sommatis S, Maccario C, Capillo MC, Grimaldi G, Alonci G, Protasoni M, Rauso R and Mocchi R. Toward physicochemical and rheological
characterization of different HA dermal fillers cross-linked with Polyethylene Glycol Diglycidyl Ether. Polymers 2021, 13, 948. https://doi.org/10.3390/polym13060948.
